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BIOPEP-UWM

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 by Piotr Minkiewicz

Description

The BIOPEP-UWM database contains sequences of biologically active peptides, taste-affecting peptides and amino acids, proteins as well as allergenic proteins The information concerning peptide, annotated in the BIOPEP-UWM database includes: sequence written in a single-letter code, information about bioactivity or taste, reference, structure written using chemical codes (SMILES, InChI and InChIKey), data about biological activity (e.g. inhibition of proteolytic enzymes) or taste, and ID numbers from other databases.
The database contains tools for determining the location of peptides in protein sequences, comparing protein sequences as precursors of bioactive or sensory peptides based on the frequency of bioactive or taste affecting fragments as a quantitative descriptor, simulating proteolysis and calculating parameters for quantitative description of predicted susceptibility to proteolysis.
Application converting peptide sequences into SMILES code is also included.

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Piotr Minkiewicz
Researcher at University of Warmia and Mazury in Olsztyn
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Piotr Minkiewicz

Researcher at University of Warmia and Mazury in Olsztyn

Recent publication concerning the BIOPEP-UWM database Oval 17

Minkiewicz P., Iwaniak A., Darewicz M., BIOPEP-UWM database of bioactive peptides: current opportunities. International Journal of Molecular Sciences, 2019, 20, Article No 5978. doi:10.3390/ijms20235978

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